by | Oct 22, 2019 | Dhavale, Dhruva, Kotzbauer, Paul, Tu, Zhude "Will", Yue, Xuyi
— Technology Description
A team of researchers at Washington University have developed and optimized highly potent PET imaging probes which are specific for the misfolded protein that is the hallmark of Parkinson’s disease and related disorders. This family of molecules was designed based on s…
by | Jul 31, 2018 | Tobin, Garry
— Technology Description: A hospital-based algorithm and associated software that is able to predict which in-patients on diabetic therapy will develop hypoglycemia. It is able to predict in real time which patients are at risk and alert MDs to start interventions to prevent possible side effects or d…
by | Jun 7, 2018 | Shaikh, Nurmohammad, Tarr, Phillip
— Primary Inventor: Phillip I. Tarr, MD
Target: GelE(mAb 8A3)
Monoclonal antibodies against E. faecalis gelatinase developed as a treatment for Crohn’s disease. E. faecalis secretes many proteins into the gastrointestinal enviroment – such as Gelatinase (GelE). GelE degrades several proteins including gelatin, collagin, hemoglobin, and bioactive peptides.…
by | Mar 27, 2018 | Song, Sheng-Kwei "Victor", Wang, Qing, Wang, Yong
— Background: Diffusion tensor imaging (DTI) has demonstrated sensitivity to detect pathologies in CNS white matter disorders. However, the capability of DTI to detect CNS white matter pathologies is confounded by the coexisting structural (crossing fibers) and pathological (inflammation associated ce…
by | Mar 10, 2018 | Hallahan, Dennis
— Technology: GRP78 is a chaperone that is part of a complex that controls the maturation of glycoproteins in the ER and senses cellular stress in normal cells. However, following radiation treatment, GRP78 is also expressed on the surface of cancer cells and has anti-apoptotic and pro-angiogenesis ac…