This is a recombinant clone of the Chikungunya LR2006 virus expressing Cre recombinase inserted downstream of a subgenomic promoter. In vitro transcription and transfection of RNA derived from this plasmid into cells will result in the generation of Chikungunya virus that expresses Cre recombinase in cells that it infects.

Publication: Young, A. R., Locke, M. C., Cook, L. E., Hiller, B. E., Zhang, R., Hedberg, M. L., … & Lenschow, D. J. (2019). Dermal and muscle fibroblasts and skeletal myofibers survive chikungunya virus infection and harbor persistent RNA. PLoS pathogens, 15(8), e1007993.