Intraocular Artificial Lenses

Tech ID: T-006771

The present hydrogel technology can be used as a lens replacement material for the permanent treatment of cataracts and presbyopia as well as a vitreous substitute. This co-polymeric hydrogel system can be reversibly converted between a hydrogel in the oxidized state and a solution in the reduced state and mimics the optomechanical properties of the native lens and vitreous. Rabbit studies using the hydrogel system as a vitreous substitute indicate that the material can be injected into the eye, undergo gelation, remain optically clear, and remain well tolerated. Long-term biocompatibility and degradation studies are in progress.

Benefits:

  • Permanent solution to cataracts, presbyopia, and vitroretinal pathologies.
  • Minimally invasive and easily deliverable through injection.
  • Can conform to fill native or potential cavities.
  • Drugs and/or particles may be added to the system.

Categories

Inventors

Contact

Richards, Jennifer

richards.j@wustl.edu

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