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Method to evaluate function of members of a gut microbiota
Patnode, Michael ; Gordon, Jeffrey
T-018760

— Technology Description Researchers at Washington University in St. Louis have developed a bead-based method to understand the functional states and metabolic capabilities of individual members of the human gut microbiota. The gut microbiota is increasingly linked to multiple aspects of human healt…

Sigma-1 targeted PET tracers
Wang, Wei ; Mach, Robert ; Tu, Zhude "Will"
T-010394

— Technology Description Researchers at Washington University in St. Louis and their colleagues have developed positron emission tomography (PET) tracers with high affinity for sigma-1 receptors. Sigma receptors have two subtypes, sigma-1 and sigma-2. Sigma-1 has high expression in the limbic and mo…

Methods to accurately measure diastolic function from echocardiogram
Shmuylovich, Leonid ; Chung, Charles ; Kovacs, Sandor
T-005426

— Technology Description Researchers in Prof. Sandor Kovacs’ laboratory developed a patented, non-invasive, load-independent method to measure the intrinsic diastolic performance of the heart. This load-independent index of filling (LIIF) can be incorporated into the software of echocardiogram…

Novel Acute Myocardial Injury Biomarker Profile
Bach, Richard ; Boyle, Walter
T-015345

— Background: Cardiovascular disease, including acute myocardial injury (AMI), is responsible for over 610,000 deaths per year in the US making it the number one cause of death. The gold standard for AMI diagnosis relies on determination of the cardiac troponin I (cTnI) plasma level. The rise in the l…

Blood-based biomarkers of Alzheimer’s disease for diagnostics and clinical trials
Ibanez, Laura ; Dube, Umber ; Cruchaga, Carlos
T-019198

— Technology Description: Researchers in Prof. Carlos Cruchaga’s laboratory have identified a sensitive and specific panel of circular RNAs (circRNA) that could be used for diagnosing, screening or monitoring patients with Alzheimer’s disease. The expression of these circRNAs tracks with …

Method to create designer stem cells for safer, more effective therapeutics
Guilak, Farshid
T-018758

— Technology Description Researchers at Washington University in St. Louis have developed a method to create designer stem cells which provide a safer, more effective cell therapy approach to treating disease. Cell-based regenerative therapies could potentially be used to treat many diseases and res…

Real-time air and water quality monitoring with AI-based data analysis and low cost sensors
Li, Jiayu ; Biswas, Pratim
T-018523

— Technology Description Prof. Pratim Biswas and colleagues have developed an artificial intelligence platform to provide accurate, low-cost analysis of air and water quality by integrating data gathered from particulate matter (PM) sensors and other sources. This technology could be used to make th…

Low-cost, high-performance materials for solar-driven membrane distillation in water treatment and desalination
Singamaneni, Srikanth ; Wu, Xuanhao ; Jiang, Qisheng ; Jun, Young-Shin
T-019047

— Technology Description Engineers in Prof. Young-Shin Jun’s laboratory and Prof. Singamaneni’s laboratory have developed high performance, stable membrane materials that can be used for photothermal membrane distillation (PMD) to purify or desalinate water with minimal input of electric…

AAVLenti-WFS1 (adeno-associated virus expressing WFS1, lentivirus expressing WFS1)
Urano, Fumihiko
T-018716

— Adeno-associated virus expressing WFS1, lentivirus expressing WFS1

Eastern Equine Encephalitis virus (EEEV) antibodies
Diamond, Michael
T-018711

— Eastern Equine Encephalitis virus (EEEV) antibodies

Crispr developed SARM1 Knockout Rat
DiAntonio, Aaron ; Milbrandt, Jeffrey
T-018728

— Crispr developed SARM1 Knockout Rat

Adhesive coated sutures for stronger musculoskeletal repairs
Thomopoulos, Stavros ; Genin, Guy ; Linderman, Stephen
T-014989

— Technology Description An interdisciplinary team at Washington University in St. Louis has developed patented adhesive-coated sutures with the potential to reduce ruptures following surgical repair of tendons and ligaments. These modified sutures are designed to minimize stress by shifting the mec…

GL-261 Single Chain Trimer cells, CL251.puro – Mouse brain tumor cell line transduced with antigen
Dunn, Gavin
T-017659

— Mouse brain tumor cell line transduced with antigen

APT1 deficient mouse
Wei, Xiaochao ; Semenkovich, Clay
T-017904

— APT1 deficient mouse

Superficieibacter electus
Andleeb, Saadia ; Burnham, Carey-Ann
T-018501

— Superficieibacter electus

Human Monoclonal Antibodies: MD.03.1H06, MD.03.1B06, MD.03.1D11, MD.031F03, MD.03.1F11, MD.03.1H01, MD.025.2H09, MD.03.1G01, MD.025.2F10, MD.025.2B07, MD.025.2G11, MD.025.1F09, MD.025.1D01, MD.025.1H07, 306.012.7.1C10, 306.012.7.1A05, 10.036.7.1B04, 10.04.7.1B03
Ellebedy, Ali
T-018756

— Human Monoclonal Antibodies: MD.03.1H06, MD.03.1B06, MD.03.1D11, MD.031F03, MD.03.1F11, MD.03.1H01, MD.025.2H09, MD.03.1G01, MD.025.2F10, MD.025.2B07, MD.025.2G11, MD.025.1F09, MD.025.1D01, MD.025.1H07, 306.012.7.1C10, 306.012.7.1A05, 10.036.7.1B04, 10.04.7.1B03

Egr1Cre;Snap25Flp mice (On deposit with Jackson Labs – Strain 033895)
Dougherty, Joseph
T-018757

— Egr1Cre;Snap25Flp mice

Cd40lg-Cre mouse
Chou, Chun ; Egawa, Takeshi
T-018831

— Cd40lg-Cre mouse

Venezuelan equine encephalitis virus (VEEV) E2 DNA plasmid
Kim, Arthur ; Diamond, Michael
T-019082

— VEEV E2 DNA plasmid

Gfrα1FloxEGFP mice
Milbrandt, Jeffrey ; Jain, Sanjay
T-017997

— Using the Cre-deletor strain Hoxb7-Cre, Washington University researchers developed transgenic mice with loxP sites flanking the gene for the glial cell line-derived neurotrophic factor (GDNF) family receptor α1 (GFRα1), which is involved in kidney tissue development. These mice were the…