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ViroCap: enhanced, efficient virome sequencing with metagenomic capture probesWylie, Todd ; Wylie, Kristine ; Storch, Gregory
T-015124
— Technology Description A team of researchers at Washington University developed “ViroCap”, a patented capture probe technique for senistive, comprehensive, in-depth metagenomics analysis vertebrate viruses. This invention could enhance traditional metagenomics shotgun sequencing (MSS) w…
Low-Power, Fast Sensors for Infrastructure‐to‐Vehicle Communications in Autonomous DrivingPochettino, Owen ; Kondapalli, Sri Harsha ; Aono, Kenji ; Chakrabartty, Shantanu
T-019014
— Engineers in Prof. Shantanu Chakrabarty’s laboratory have developed an RFID embedded sensor system for infrastructure-to-vehicle (I2V) communications that uses near-zero standby energy and offers the robust performance of actively powered communications. This technology is designed to provide …
Pressure recovery ratio (PRR) index for real-time assessment of heart failureZhang, Weixiong ; Shmuylovich, Leonid ; Chung, Charles ; Kovacs, Sandor
T-007562
— Technology Description Researchers in the Cardiovascular Biophysics Laboratory at Washington University developed a patented, real-time, automated index to reliably detect delayed relaxation during cardiac catheterization diagnostics. This technique, called pressure recovery ratio (PRR), serves as…
Low-cost, environmentally friendly synthesis of delta-MnO2 nanosheets for battery cathodes, catalysts and remediationJung, Haesung ; Jun, Young-Shin
T-018510
— Technology Description Engineers in Prof. Young-Shin Jun’s laboratory have developed a cost-effective, fast, green chemistry process to produce birnessite (δ-MnO2) nanosheets with naturally abundant resources. This method uses sunlight and nitrate to oxidize Mn2+ (aq) to Mn (IV) and ha…
Machine learning methods for real-time MRI image processing: MRI-only radiation treatment planning and improving MR image resolutionMutic, Sasa ; Zhang, Hao ; Green, Olga ; Park, Chunjoo (Justin)
T-018522
— Technology Description A team of researchers at Washington University School of Medicine developed deep learning image processing techniques to improve MRI diagnostics and potentially enable faster, more precise MRI-guided radiation therapy without exposing patients to radiation from CT imaging. S…
Ultrasound-guided diffuse optical tomography for fast, low-cost functional imaging of breast lesionsMostafa, Atahar ; Zhu, Quing
T-018800
— Technology Description Prof. Quing Zhu and colleagues have pioneered a compact, low-cost ultrasound-guided optical tomography system designed to differentiate between benign and malignant breast lesions and reduce the need for costly and invasive biopsies. This technology enables fast, robust imag…
Antibodies to TroponinLadenson, Jack
T-000093
— Antibody codes: 2B1.9 (3268) and 2F6.6 Publication: Bodor GS, Porter S, Landt Y, Ladenson JH. Development of monoclonal antibodies for an assay of cardiac troponin-I and preliminary results in suspected cases of myocardial infarction. Clin Chem. 1992 Nov;38(11):2203-14. Antibody codes: 5…
Antibody to SPRR3Young, Pampee ; Ladenson, Jack
T-004462
— Analyte: Small proline rich protein 3 (gene SPRR3) Antibody codes: 3E9.1 (4587), 4G3.1 (4563), and 2F10.2 (4604) Publications:
microRNA biomarker and drug target for ALS and other motor neuron diseasesHyman, Theodore ; Koval, Erica ; Hoye, Mariah ; Dougherty, Joseph ; Miller, Timothy
T-015167
— Prof. Timothy Miller and colleagues have identified a motor neuron-specific, drug responsive microRNA (miR-218) that reflects the pathology of amyotrophic lateral sclerosis (ALS). This biomarker could be a target for therapeutic intervention or a proxy for motor neuron health and survival, including…
Biomarkers for Alzheimer’s Disease and Brain InjuryLaterza, Omar ; Modur, Vijay ; Landt, Yvonne ; Ladenson, Jack
T-004414
— Technology Description Researchers in Prof. Jack Ladenson’s laboratory have discovered biomarkers and associated antibodies for Alzheimer’s disease (AD) that could be used for early/presymptomatic diagnosis or in clinical trials for AD drugs. This patented technology is based on the i…
Antibody to CalmodulinLadenson, Jack
T-000190
— Analyte: Calmodulin Antibody code: 2D1.15 Publication: Sacks DB, Porter SE, Ladenson JH, McDonald JM. Monoclonal antibody to calmodulin: development, characterization, and comparison with polyclonal anti-calmodulin antibodies. Anal Biochem. 1991 May 1;194(2):369-77
Antibody to MyoglobinLadenson, Jack
T-000126
— Analyte: Myoglobin Antibody codes: Notes: Suitable for two-site immunoassay Publication: Silva DP Jr, Landt Y, Porter SE, Ladenson JH. Development and application of monoclonal antibodies to human cardiac myoglobin in a rapid fluorescence immunoassay. Clin Chem. 1991 Aug;37(8):1356-64.
Antibodies to transferrin receptorPorter, Sharon ; Ladenson, Jack
T-000757
— Analyte: Transferrin Receptor (CD71) Antibody codes: 2B7.4 (4065) and 2F6.3 (4077) Publications:
User-friendly methods to detect artifacts in super-resolution microscopyNehorai, Arye ; Mazidisharfabadi, Hesamaldin ; Lew, Matthew
T-019008
— Engineers at Washington University have devised an automated system to enhance super-resolution microscopy images by detecting and quantifying image artifacts using no a priori information. This project stems from the advanced imaging research in Prof. Matthew Lew’s laboratory that includes op…
Antibiotic-sparing small molecule therapy for urinary tract infection and other Gram-negative pathogensPinkner, Jerome ; Yuan, Peng ; Omattage, Natalie ; Dodson, Karen ; Hultgren, Scott
T-018046
— Technology Description Researchers in Prof. Scott Hultgren’s laboratory have discovered an antibiotic-sparing method for treating infections from E. coli and other Gram-negative bacteria. This approach is designed to block pathogens from colonizing their host by using small molecule inhibito…
Antibodies against Toxoplasma gondii proteins ROP1, ROP5, GRA7Sibley, Laurence
T-018971
— Polyclonal or monoclonal antibodies against Toxoplasma gondii proteins (ROP1, ROP5, GRA7) Mouse anti-body ROP1 publication: Localization of a Toxoplasma gondii Rhoptry Protein by Immunoelectron Microscopy During and After Host Cell Penetration Polyclonal rabbit antibody ROP5 publication: Virulence…
Chikungunya Monoclonal AntibodiesFremont, Daved ; Diamond, Michael
T-010020
— Description: Monoclonal antibodies that react with and/or neutralize Chikungunya virus Publication:
Hamster Monoclonal IgG Antibody against Mouse IFN-AlphaSheehan, Kathleen ; Schreiber, Robert
T-012056
— Description: TIF-3C5- Armenian hamster monoclonal antibody reactive with murine Type I Interferons, including IFN alpha A, 1, 4, 5, 11 and 13 but not IFNbeta. This mAb can block functional activity. Publication:
Hamster Monoclonal IgG2a Antibody against Mouse IFN-BetaSheehan, Kathleen ; Schreiber, Robert
T-012057
— Description: HDbeta-4A7- mouse IgG2a monoclonal antibody reactive with murine Interferon-beta. This mAb has neutralizing activity. Publication:
Chinese Hamster Ovary Cell Line Expressing Human Follicle-Stimulative Hormone (FSH) / Human Luteinizing Hormone (FSH)Boime, Irving
T-012328
— Description: Cell lines individually expressing the following hormones: Lutenizing hormone (LH), Thyrotropin (TSH) and Follitropin (FSH). Publications:
