— Published Date: 5/14/2025 Value Proposition: Robust and reliable biomarker to accurately predict patient response to PARP inhibitors and platinum chemotherapy for high grade serous ovarian cancer. Technology Description Researchers at Washington University in St. Louis have developed an automat…
— Published Date: 5/14/2025 Value proposition: Self-sustaining chimeric macrophages as a novel approach to target amyloid plaques resulting in improved efficacy and survival in patients. Technology Description Researchers from Washington University in St. Louis have engineered macrophages to expre…
— Published Date: 5/14/2025 Value proposition: Using CAR T-cells to treat Alzheimer’s disease and other neurodegenerative diseases through Ab-specific activation. Technology Description While CD4+ (helper or effector) T-cells play complex roles in the pathophysiology of Alzheimer’s …
— Published Date: 5/14/2025 Value proposition: Novel ASOs that increase key protein production to limit neurodegeneration caused by ALS and frontotemporal dementia (FTD). Technology Description TDP-43 pathology is present in ~97% of ALS, ~50% of FTD, and frequently observed in other neurodegenerat…
— Published Date: 5/15/2025 Value proposition: Novel analgesic compounds that block CaV3.2 currents in nociceptive dorsal root ganglion neurons in order preemptively treat pain in subjects, unlike other products that are continuously administered post onset of pain. Technology Description Resear…
— Published Date: 5/14/2025 Value Proposition: Method that uses gene-therapy to detect limb-girdle muscular dystrophy (LGMD) type 4R/2E. Technology Description Researchers at Washington University in St. Louis have developed a method of predicting limb-girdle muscular dystrophy (LGMD) type 4R/2…
— Published Date: 12/21/24 Value proposition: A cost-effective, drug-based therapy targeting the endothelin B receptor (ETBR) to promote peripheral nerve regeneration, offering improved recovery and compatibility with existing treatments. Technology Description Researchers at Washington University…
— Published Date: 5/13/2025 Value Proposition: A novel approach to repurposing FDA-approved anti-epileptic drugs to treat brain and nerve tumors associated with neurofibromatosis type I, offering a faster, cost-effective pathway to address an urgent unmet medical need. Technology Description Neuro…
— Published Date: 5/13/2025 Value Proposition: Promotion of recovery and reduction of neuronal damage following nerve injury, first T cell approach to neurological disorders. Technology Description Traumatic injuries to the spinal cord or the brain currently have limited treatment options, particu…
— Published Date: 5/13/2025 Value proposition: New therapeutic modality that uses CNS self-peptides to treat autoimmune diseases, reducing neuroinflammation damage in an organ-specific manner. Technology Description Autoimmune diseases continue to debilitate countless individuals, increasing healt…
— Published Date: 12/24/2024 Value proposition: An advanced CAR-T cell therapy engineered to reduce T cell exhaustion, enhancing durability and effectiveness in cancer treatment by overcoming one of the leading causes of long-term treatment failure. Technology Description Researchers at Washington…
— Published Date: 5/13/2025 Value Proposition: Plasma cell-free transcripts that can be used as biomarkers to aid in the diagnosis and monitoring of Parkinsons Disease. Technology Description Researchers at Washington University in St. Louis have developed a panel of cell free RNA (cfRNA) biomark…
— Published Date: 5/10/2025 Value Proposition: Method that uses plasma cfRNAs to differentiate Alzheimer’s disease from healthy controls. Technology Description Researchers at Washington University in St. Louis have developed a series of models using blood-based biomarkers to detect Alzheimer …
— Published Date: 5/10/2025 Value Proposition: Diagnostic method that uses the patient’s PBMCs acquired before or immediately after the onset of IL-23 therapy to determine the presence of signatures indicative of long-term IL-23 response. Technology Description Researchers at Washington Univ…
— Published Date: 4/29/2025 Value Proposition: Novel biomarker that can be used as a diagnostic to identify glaucoma severity or progression in patients. Technology Description Researchers at Washington University in St. Louis have identified a novel biomarker, GDF15, for glaucoma that can detect …
— Published date: 3/14/2025 WHICH-A.R.T: Method for Accurately Detecting Male Infertility Value Proposition: Fertility treatment designed to quickly and accurately detect the fertilization capacity of sperm. Technology Description Researchers at Washington University in St. Louis have developed…
— Value Proposition: Engineered iNKT cells with potential as a “universal” source of immune effector cells to treat cancer. Technology Description Researchers at Washington University in St. Louis have developed a new composition of matter that uses gene-edited invariant natural kill…
— Published Date: 2/14/2025 Value Proposition: Speech synthesizer that uses adversarial audio to prevent the creation of deepfakes. Technology Description Researchers at Washington University in St. Louis have developed a computer implemented method for generating audio content that introduces per…
— Published Date: 2/14/2025 Value Proposition: Portable and deployable platform that uses an AI-enabled, nanoparticle-based e-nose to sense explosive volatile organic compounds. Technology Description Researchers at Washington University in St. Louis have developed a low-power electronic nose that…
— Published date: 1/29/2025 Value Proposition: New chemical matter that blocks protein synthesis, eliminating infection and providing improved treatment for Toxoplasmosis. Technology Description Researchers at Washington University in St. Louis have identified a new chemical matter that can inh…
