— Technology Description Prof. Quing Zhu and colleagues have pioneered a compact, low-cost ultrasound-guided optical tomography system designed to differentiate between benign and malignant breast lesions and reduce the need for costly and invasive biopsies. This technology enables fast, robust imag…

— Antibody codes: 2B1.9 (3268) and 2F6.6 Publication: Bodor GS, Porter S, Landt Y, Ladenson JH. Development of monoclonal antibodies for an assay of cardiac troponin-I and preliminary results in suspected cases of myocardial infarction. Clin Chem. 1992 Nov;38(11):2203-14. Antibody codes: 5…

— Analyte: Small proline rich protein 3 (gene SPRR3) Antibody codes: 3E9.1 (4587), 4G3.1 (4563), and 2F10.2 (4604) Publications:

— Prof. Timothy Miller and colleagues have identified a motor neuron-specific, drug responsive microRNA (miR-218) that reflects the pathology of amyotrophic lateral sclerosis (ALS). This biomarker could be a target for therapeutic intervention or a proxy for motor neuron health and survival, including…

— Technology Description Researchers in Prof. Jack Ladenson’s laboratory have discovered biomarkers and associated antibodies for Alzheimer’s disease (AD) that could be used for early/presymptomatic diagnosis or in clinical trials for AD drugs. This patented technology is based on the i…

— Analyte: Calmodulin Antibody code: 2D1.15 Publication: Sacks DB, Porter SE, Ladenson JH, McDonald JM. Monoclonal antibody to calmodulin: development, characterization, and comparison with polyclonal anti-calmodulin antibodies. Anal Biochem. 1991 May 1;194(2):369-77

— Analyte: Myoglobin Antibody codes: Notes: Suitable for two-site immunoassay Publication: Silva DP Jr, Landt Y, Porter SE, Ladenson JH. Development and application of monoclonal antibodies to human cardiac myoglobin in a rapid fluorescence immunoassay. Clin Chem. 1991 Aug;37(8):1356-64.

— Analyte: Transferrin Receptor (CD71) Antibody codes: 2B7.4 (4065) and 2F6.3 (4077) Publications:

— Engineers at Washington University have devised an automated system to enhance super-resolution microscopy images by detecting and quantifying image artifacts using no a priori information. This project stems from the advanced imaging research in Prof. Matthew Lew’s laboratory that includes op…

— Polyclonal or monoclonal antibodies against Toxoplasma gondii proteins (ROP1, ROP5, GRA7) Mouse anti-body ROP1 publication: Localization of a Toxoplasma gondii Rhoptry Protein by Immunoelectron Microscopy During and After Host Cell Penetration Polyclonal rabbit antibody ROP5 publication: Virulence…

— Description: Monoclonal antibodies that react with and/or neutralize Chikungunya virus Publication:

— Description: TIF-3C5- Armenian hamster monoclonal antibody reactive with murine Type I Interferons, including IFN alpha A, 1, 4, 5, 11 and 13 but not IFNbeta. This mAb can block functional activity. Publication:

— Description: HDbeta-4A7- mouse IgG2a monoclonal antibody reactive with murine Interferon-beta. This mAb has neutralizing activity. Publication:

— Description: Cell lines individually expressing the following hormones: Lutenizing hormone (LH), Thyrotropin (TSH) and Follitropin (FSH). Publications:

— Description: Plasmids encoding LDLR and TFP developed by Dr. David Holtzman and colleagues. Note: Contact for additional information. Plasmid maps are available.

— Description: LDLR transgenic mice Publication:

— Description: Publications:

— Description: P301Stau/E4 cross-bred mice Publication: Shi Y, Yamada K, Liddelow SA, Smith ST, Zhao L, Luo W, Tsai RM, Spina S, Grinberg LT, Rojas JC, Gallardo G, Wang K, Roh J, Robinson G, Finn MB, Jiang H, Sullivan PM, Baufeld C, Wood MW, Sutphen C, McCue L, Xiong C, Del-Aguila JL, Morris JC, Cru…

— Description: 2ftgh-ISRE-CBG99 cell line- a report line for interferon stimulation. To create these cells the inventors generated a report plasmid of interferon-stimulated response element (5xISRE)-driven luciferase, and co-transfected this vector together with pPUR plasmid into the human 2ftgh fibr…

— Description: Calcium Carbonate nanoparticles for normalizing tumor microenvironment Publication: Som A, Raliya R, Tian L, Akers W, Ippolito JE, Singamaneni S, Biswas P, Achilefu S. Monodispersed calcium carbonate nanoparticles modulate local pH and inhibit tumor growth in vivo. Nanoscale. 2016 Jul …