by | Nov 7, 2019 | Colonna, Marco
— Target: CD155 is a adhesion receptor, orginally known as the cellular receptor for Polio Virus.
Notes: Clone name is SK II 4.3
Information on antibody against poliovirus receptor (CD155)
Herein, we describe the generation of a murine antibody that recognizes poliovirus receptor (CD155). We made this antibody by immunizing mice with SK-N-S1 human neuroblastoma cells. We then validated this antibody using flow cytometry.
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by | Nov 6, 2019 | Colonna, Marco
— Target: CD96 is a T cell-specific receptor indicative of T cell activation.
Notes: Clone name NK92.39.1. For use in flow cytometry.
Researchers generated the antibodies by immunizing mice with NK92 cells and selected hybridomas that plocked binding of PVR to NK92. These antibodies have been used to study natural killer cell target cell adhesion.
Publication: Cutting Edge: CD96 (Tactile) Promotes NK Cell-Target Cell Adhesion by …
by | Oct 31, 2019 | Colonna, Marco
— Target: NKp44 is a novel triggering surface molecular specifcially expressed by activated natural killer cells.
Notes: Clone name 448.189 Marco Colonna, MD
Inventors generated NKp44 monocolonal antibodies by immunizing mice with a NKp44-human crystallizable fragment (Fc) fusion protein. The antibodies have been used to study innate and adaptive immune responses.
Publication: Paradoxic inhibition of human natural interferon-producing cells by the activ…
by | Oct 22, 2019 | Colonna, Marco, Ulland, Tyler
— Background: Alzheimer’s disease (AD) is the 6th leading cause of death in the United States, and yet causation of the disease is poorly understood and targets for therapeutic intervention are still being identified. Recently, mutations in the immune receptor TREM2 have been found to be strongl…
by | Oct 22, 2019 | Colonna, Marco
— Target: Cluster of Differentiation, a.k.a. Neural Cell Adhesion Molecule.
Notes: Clone name is DCN.70.
by | Oct 22, 2019 | Colonna, Marco
— Target: Retinoic Acid Early 1 Delta protein.
Notes: Clone Charlotte O1.23.
