by | Mar 10, 2018 | Goodenough, Ursula, Goodson, Carrie
— There is currently keen interest in cultivating eukaryotic algae as sources of triacylglycerides (TAGs) to be converted into diesel and jet transportation fuel. Recent studies from numerous labs have shown that when stressed by nitrogen (N)-starvation, Chlamydomonas reinhardtii produce TAGs that ca…
by | Mar 10, 2018 | Alvarado, David, Dobbs, Matthew, Gurnett, Christina, Haller, Gabriel
— Background: A DNA point mutation is a single nucleotide base substitution, insertion, or deletion in a gene sequence. Point mutations are responsible for several diseases including cystic fibrosis, sickle-cell disease, polycystic kidney disease, microcephaly, and Crohn’s disease. The study on …
by | Mar 10, 2018 | Corbo, Joseph, Havranek, James, Mitra, Robi, Myers, Connie, Qi, Zongtai, Zhang, Chi
— Background: The function of enzymes involved in homologous recombination can be exploited in the field of genetic engineering in order to generate mutations of interest. However, this machinery is not functionally efficient in post mitotic or terminally differentiated cells. Viral gene therapy techn…