by | Sep 17, 2021 | Crowley, Jan, Henderson, Jeffrey P., Robinson, John
— Technology Description
Researchers in Prof. Jeffrey Henderson’s laboratory have developed a method of analyzing metabolic biomarkers from fecal samples to more accurately identify C. difficile infection (CDI) and distinguish between symptomatic and asymptomatic colonization. CDI is currently …
by | Sep 9, 2021 | Choi, Kyunghee, Kabir, Ashraf Ul, Krchma, Karen
— Technology Description
Researchers in Kyunghee Choi’s lab at Washington University in St. Louis have identified a novel target, Myct1, that modulates tumor angiogenesis and anti-tumor immune response. Myct1 inhibition with siRNA blocks angiogenesis and promotes infiltration of cytotoxic T ly…
by | Sep 6, 2021 | Azab, Abdel Kareem, Azab, Feda, de la Puente Garcia, Maria del Pilar
— Background
External Beam Radiotherapy (EBR) is commonly used after surgical removal of a tumor (in e.g. a breast-conserving surgery) to control or kill malignant cells. The lack of selectivity due to irradiation of whole or partial organs from outside the body, however, is potentially damaging to t…
by | Jun 24, 2021 | Ances, Beau, Butt, Omar, DiPersio, John, Ghobadi, Armin
— Technology Description:
Researchers at Washington University in St. Louis have developed a biomarker screening assay to predict which patients receiving CAR T cell therapy will experience neurotoxicity. Patients can be screened well in advance of receiving the T cell therapy with a simple serum as…
by | Jun 11, 2021 | Shen, Hua
— Technology Description:
A team of researchers at Washington University has developed a cell-free, nano-sized extracellular vesicle (EV/exosome) system to enhance repair of soft musculoskeletal tissue. This technology leverages the natural anti-inflammatory effects of adipose-derived stem cells (ASC…