by | Jul 13, 2020 | Ory, Daniel, Peterson, Linda, Schaffer, Jean
— Technology Description
A team of researchers has developed a high throughput, FDA-compliant assay to predict coronary heart disease and mortality in the general population 6-10 years before the onset of disease. This fully validated two-dimensional liquid chromatography-tandem mass spectrometry (L…
by | Jul 9, 2020 | Gong, Yong-feng, Hou, Jianghui
— Disease indication: metabolic disorders including insulin resistance and diabetic nephropathy
Drug format: chemically modified synthetic microRNA (miRNA)
Drug class: first-in-class for metabolic disease
Research stage and Preliminary data:
Target: miR-29 mimics can increase the gene expressio…
by | Jun 26, 2020 | Azab, Abdel Kareem, Federico, Cinzia, Schwarz, Julie, Sun, Jennifer
— Technology Description
Researchers in Prof. Kareem Azab’s laboratory have developed a fast, localized drug delivery system designed to maximize anti-tumor efficacy and reduce side effects by delivering chemotherapy directly to cervical tumors.
The current standard-of-care treatment regimen …
by | Jun 9, 2020 | Chaudhuri, Aadel, Maher, Christopher, Pachynski, Russell
— Technology Description
A team of researchers at Washington University has developed “EnhanceAR-Seq”, a circulating tumor DNA (ctDNA) assay that predicts which patients are at high risk for developing resistance to androgen receptor (AR)-directed treatment for metastatic prostate cancer…
by | Jun 4, 2020 | Curiel, David, Diamond, Michael, Dmitriev, Igor, Hassan, Ahmed
— Technology Description
Researchers at Washington University in St. Louis have developed a chimpanzee adenovirus-based vaccine for COVID-19. COVID-19, the clinical syndrome caused by SARS-CoV-2 infection, has had extensive morbidity and mortality impacts and destabilized society. There is an urg…