by | Oct 22, 2019 | Berezin, Mikhail, Binkley, Michael, Meacham, John
— Technology Description:
Methods and devices used for acoustophoresis of biologics have been developed and allow for more than 10,000 fold throughput than existing acoustophoretic devices.
Applications:
1. Isolation of cells in low abundance (immune cells, circulating tumor cells) from whole bloo…
by | Oct 22, 2019 | Klechevsky, Eynav
— Background
Dendritic cells (DCs) are antigen-presenting cells that are essential to the adaptability of the immune system. Several subsets of DCs have been identified in tissues that interface with the environment (e.g. skin, mucosal lining). While the role of specific DC subsets are unknown, DCs p…
by | Oct 22, 2019 | Crimmins, Dan, Gaut, Joseph, Ladenson, Jack
— This novel immunohistochemical marker would be a valuable diagnostic aid to the practicing surgical pathologist who is confronted with this particular diagnostic challenge. Companies may license this antibody for clinical testing, or cases may be referred to Washington University for subspecialty c…
by | Oct 22, 2019 | Apte, Rajendra
— Technology Description
Researchers in Prof. Rajendra Apte’s laboratory developed novel methods for treating macular degeneration and other eye diseases by targeting a cholesterol transport pathway involved in the formation of new blood vessels. Age-related macular degeneration (AMD) is a lea…
by | Oct 22, 2019 | Xu, Mai
— Background: In the US alone, 154,000 new cases of colorectal cancer (CRC) are diagnosed each year. Unfortunately, a third of those patients will die due to diagnosis at late stages – the 5-year survival rate is 11%, compared to 91% for those who are diagnosed with only localized CRC. A colonos…