by | Apr 16, 2020 | Guilak, Farshid
— Technology Description
Researchers at Washington University in St. Louis have developed a method to create designer stem cells which provide a safer, more effective cell therapy approach to treating disease. Cell-based regenerative therapies could potentially be used to treat many diseases and res…
by | Feb 20, 2020 | Dougherty, Joseph, Hoye, Mariah, Hyman, Theodore, Koval, Erica, Miller, Timothy
— Prof. Timothy Miller and colleagues have identified a motor neuron-specific, drug responsive microRNA (miR-218) that reflects the pathology of amyotrophic lateral sclerosis (ALS). This biomarker could be a target for therapeutic intervention or a proxy for motor neuron health and survival, including…
by | Feb 20, 2020 | Ladenson, Jack, Young, Pampee
— Analyte: Small proline rich protein 3 (gene SPRR3)
Antibody codes: 3E9.1 (4587), 4G3.1 (4563), and 2F10.2 (4604)
Publications:
by | Jan 31, 2020 | McAlinden, Audrey, O'Keefe, Regis, Shen, Jie
— A team of researchers at Washington University in St. Louis has identified an epigenetic pathway and two therapeutic targets that could be used to prevent cartilage loss and counteract the mechanism underlying osteoarthritis. The inventors have seen promising results in a mouse model of arthritis us…
by | Jan 21, 2020 | Liu, Hui, Rosenberg, Adam, Tu, Zhude "Will", Yue, Xuyi
— Technology Description
Researchers at Washington University in St. Louis have developed sphingosine 1-phosphate receptor 1 (S1P1)-specific PET tracers. Sphingosine 1-phosphate receptors are G-protein coupled receptors, with five subtypes denoted S1P1-5, that have key functions in immune, inflammat…