Design and Development of Organomedicinals for Imaging and Treatment of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia (FTD)

— Background

Frontotemporal Dementia (FTD) is the second most common form of non-Alzheimer’s dementia in the population under 65 years old. FTD represents approximately 20% of all dementias and onset normally appears in the mid to late 50s. Clinically FTD is characterized by a progressive neur…

Mobile PET imaging system

— Background

PET scanners are valued for their ability to provide whole-body functional and anatomic information, important in the diagnoses and management of metabolic conditions. However, there is currently a need in the market for a smaller imaging system that can be used for point-of-care applica…

Multifunctional chemical agents for metal chelation, positron emission tomography (PET) imaging, fluorescence imaging, and amyloid plaque clearance in Alzheimer’s disease

— Alzheimer’s disease (AD) is characterized by the deposition of amyloid plaques containing the amyloid beta (Aβ) peptide. Currently, no treatment is available for AD. Metal ion interactions of the Aβ peptide are believed to help formation of toxic aggregates. Developing chemical compo…

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