Antibodies to transferrin receptor
— Analyte: Transferrin Receptor (CD71)
Antibody codes: 2B7.4 (4065) and 2F6.3 (4077)
Publications:
Epigenetic drug targets to treat or prevent osteoarthritis and cartilage degradation
— A team of researchers at Washington University in St. Louis has identified an epigenetic pathway and two therapeutic targets that could be used to prevent cartilage loss and counteract the mechanism underlying osteoarthritis. The inventors have seen promising results in a mouse model of arthritis us…
S1P1-targeted PET tracers
— Technology Description
Researchers at Washington University in St. Louis have developed sphingosine 1-phosphate receptor 1 (S1P1)-specific PET tracers. Sphingosine 1-phosphate receptors are G-protein coupled receptors, with five subtypes denoted S1P1-5, that have key functions in immune, inflammat…
Armenian Hamster Anti-Mouse Tapasin Antibody, clone 5D3
— Target: Amino acids 11-34 of mouse tapasin.
Application(s): Western Blotting
Armenian hamster mAb (5D3) was produced to peptide EDAGGGGLSKKPATLLLRH GPRGP, representing residues 11–34 on mouse Tapasin (TPN) (44). TPN mAb was found to be specific for mouse TPN, as determined in a Western blot analysis of cell lysates of .221 (human TPN-positive) cells, .220 (human TPN-n…
Armenian Hamster Anti-Mouse Properdin Monoclonal Antibody (clone H4)
— Target: Full length mouse properdin
Application(s): Western blot and immunofluorescence
Two functional properties of one of the two hamster antibodies have been examined, the H4 subclone of the 3D12 clone. In experiments the H4 antibody was used to identify mouse properdin present in histological sections, to block mouse properdin function in vitro, and to ameliorate complement alterna…
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