by | Jul 27, 2020 | Apte, Rajendra, Van Stavern, Gregory
— Technology Description
Researchers at Washington University in St. Louis have developed a non-invasive screening method using optical coherence tomography angiography (OCTA) to detect Alzheimer’s disease (AD) at the early, preclinical stage. AD is characterized by progressive memory loss, be…
by | May 28, 2020 | Guruswami, Sundaram, Sharma, Vijay, Sivapackiam, Jothilingam
— Technology Description
Researchers at Washington University in St. Louis have developed PET radiotracers to image amyloid beta (A-beta) at early stages of Alzheimer’s Disease (AD). For AD treatment to be effective, it may have to be administered during the preclinical stage. As such, there i…
by | May 5, 2020 | Mach, Robert, Tu, Zhude "Will", Wang, Wei
— Technology Description
Researchers at Washington University in St. Louis and their colleagues have developed positron emission tomography (PET) tracers with high affinity for sigma-1 receptors. Sigma receptors have two subtypes, sigma-1 and sigma-2. Sigma-1 has high expression in the limbic and mo…
by | Apr 27, 2020 | Cruchaga, Carlos, Dube, Umber, Ibanez, Laura
— Technology Description:
Researchers in Prof. Carlos Cruchaga’s laboratory have identified a sensitive and specific panel of circular RNAs (circRNA) that could be used for diagnosing, screening or monitoring patients with Alzheimer’s disease. The expression of these circRNAs tracks with …
by | Feb 20, 2020 | Ladenson, Jack, Landt, Yvonne, Laterza, Omar, Modur, Vijay
— Technology Description
Researchers in Prof. Jack Ladenson’s laboratory have discovered biomarkers and associated antibodies for Alzheimer’s disease (AD) that could be used for early/presymptomatic diagnosis or in clinical trials for AD drugs.
This patented technology is based on the i…