by | Oct 22, 2019 | Fu, Yabo, Yang, Deshan
— Technology Description
Researchers in Prof. Deshan Yang’s laboratory have developed a deep-learning method for fast, robust, automated MRI segmentation to expedite treatment planning for patients undergoing MRI-guided adaptive radiotherapy (MR-IGART). Specifically, this technology utilizes a…
by | Oct 22, 2019 | Blumer, Kendall, Onken, Michael
— Disease indication – Uveal melanoma and other G protein-driven disorders, including other cancers (certain vascular tumors, colon, lung, adenocarcinoma, skin melanoma, thyroid adenoma), cholera and Sturge-Weber Syndrome
Drug format – small molecule (FR900359, a bioavailable inhibitor of…
by | Oct 22, 2019 | Grigsby, Perry, Zoberi, Jacqueline
— Technology Description
Radiation oncologists at Washington University in St. Louis have developed a patented plastic sheath applicator device to improve treatment planning and tumor targeting in image-guided brachytherapy (IGBT) for uterine and cervical cancer. Currently, high-dose rate brachyther…
by | Oct 22, 2019 | Curiel, David
— Disease indication – Cancer
Drug format – Adenoviral vector for immunotherapy/dendritic cell therapy
Drug class – Improvement
Research stage and Preliminary data:
Target – Carbohydrate biomarkers of cancer
Background:
Dendritic cells (DCs) are potent antigen presenting cell…
by | Oct 22, 2019 | Klechevsky, Eynav
— Background
Dendritic cells (DCs) are antigen-presenting cells that are essential to the adaptability of the immune system. Several subsets of DCs have been identified in tissues that interface with the environment (e.g. skin, mucosal lining). While the role of specific DC subsets are unknown, DCs p…