by | May 7, 2021 | Barrow, Alexander, Colonna, Marco
— Technology Description
Researchers in Prof. Marco Colonna’s laboratory have identified a receptor-ligand interaction that could be harnessed to activate the innate immune system to treat cancer or enhance the response to vaccines for infectious disease. Specifically, platelet-derived growth f…
by | Apr 26, 2021 | Chapman Jr., William "Will Jr", Leng, Xiandong, Mutch, Matthew, Uddin, Shihab, Zhu, Quing
— Technology Description:
Researchers led by Quing Zhu at Washington University have developed a method for imaging rectal tumors using photoacoustic microscopy and ultrasound with a machine learning component. This method is better able to differentiate residual cancer from healthy tissue following…
by | Feb 9, 2021 | An, Hongyu, Eldeniz, Cihat
— Technology Description
Researchers in Prof. Hongyu An’s laboratory have developed a new image processing system for faster acquisition of motion-corrected MR or PET/MR images. This technology could be expanded to multiple sampling schema to correct both respiratory and cardiac motion.
Liv…
by | Jan 29, 2021 | Mitra, Robi, Moudgil, Arnav, Wilkinson, Michael Nathaniel
— Technology Description
Researchers in Robi Mitra’s lab at Washington University in St. Louis have developed a method to increase the sensitivity of leukemias to chemotherapy by pre-treatment with a BET inhibitor. BET inhibitors convert stem-like leukemia cells to a more differentiated state …
by | Jan 15, 2021 | Amatya, Parmeshwar, Carter, Alun, Cooper, Matthew, DiPersio, John
— Technology Description
A team of researchers, led by John DiPersio and Matthew Cooper at Washington University in St. Louis, have identified a small molecule kinase inhibitor capable of mitigating cytokine release syndrome following CAR-T cell therapy. PI3K inhibitors can suppress production of IL-…