by | May 5, 2020 | Mach, Robert, Tu, Zhude "Will", Wang, Wei
— Technology Description
Researchers at Washington University in St. Louis and their colleagues have developed positron emission tomography (PET) tracers with high affinity for sigma-1 receptors. Sigma receptors have two subtypes, sigma-1 and sigma-2. Sigma-1 has high expression in the limbic and mo…
by | Apr 30, 2020 | Chung, Charles, Kovacs, Sandor, Shmuylovich, Leonid
— Technology Description
Researchers in Prof. Sandor Kovacs’ laboratory developed a patented, non-invasive, load-independent method to measure the intrinsic diastolic performance of the heart. This load-independent index of filling (LIIF) can be incorporated into the software of echocardiogram…
by | Apr 27, 2020 | Cruchaga, Carlos, Dube, Umber, Ibanez, Laura
— Technology Description:
Researchers in Prof. Carlos Cruchaga’s laboratory have identified a sensitive and specific panel of circular RNAs (circRNA) that could be used for diagnosing, screening or monitoring patients with Alzheimer’s disease. The expression of these circRNAs tracks with …
by | Apr 16, 2020 | Guilak, Farshid
— Technology Description
Researchers at Washington University in St. Louis have developed a method to create designer stem cells which provide a safer, more effective cell therapy approach to treating disease. Cell-based regenerative therapies could potentially be used to treat many diseases and res…
by | Apr 8, 2020 | Genin, Guy, Linderman, Stephen, Thomopoulos, Stavros
— Technology Description
An interdisciplinary team at Washington University in St. Louis has developed patented adhesive-coated sutures with the potential to reduce ruptures following surgical repair of tendons and ligaments. These modified sutures are designed to minimize stress by shifting the mec…