Machine learning method for fast, reliable quality assurance of patient imaging in radiation therapy or computer-aided detection

— Technology Description

A team of researchers at Washington University has created a machine learning method to quickly and reliably validate patient contours in digital medical images for radiation therapy and computer aided image analysis.

Currently, automated contouring tools for delineating tu…

Armenian hamster anti-mouse TCR Vb 8.3 IgG3 monoclonal antibody (clone 1B3.3)

— Target: Full length mouse Vb 8.3 TCR but not 8.1 or 8.2. Vb 8.3.

Application: Flow cytometry

This antibody was made by immunizing Armenian hamsters. It was used to study the mechanisms that act to keep only one functional TCR beta-chain per cell and the effect of selecting ligand density on positive selection and endogenous receptor usage in mice.

Publication: TCR transgenic mice in which …

Treatments for Wolfram syndrome

— Technology Description

Dr. Fumihiko Urano at Washington University in St. Louis (WUSTL) and colleagues have developed therapeutic strategies to treat Wolfram syndrome. Wolfram syndrome is a rare, life-threating, genetic disorder characterized by insulin-dependent diabetes mellitus, diabetes insipi…

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