by | Aug 21, 2020 | Weihl, Conrad
— Transgenic mouse strain designed and developed by Dr. Conrad Weihl with a mutation of the DNAJB6 gene at the F90I protein. This homologous with the human form of muscular dystrophy with patients having a genetic variant at the F89I protein.
by | Jul 29, 2020 | Diamond, Marc, Shao, Jieya
— Technology Description
Researchers at Washington University in St. Louis have developed a prognostic biomarker that can be used to predict response to genotoxic chemotherapy for patients with basal-like/triple-negative breast cancer. Basal-like/triple-negative breast cancer is considered to be mor…
by | Jul 20, 2020 | Arora, Vivek, Bolzenius, Jennifer
— MCB6A organoids generate urothelial tumors with features similar to the basal-squamous subtype of urothelial carcinoma, the most common bladder cancer. MCB6A harbors 1,524 mutations, including mutations in Kdm6a and Trp53.
Publication: CD4+ T cells induce rejection of urothelial tumors after imm…
by | Apr 6, 2020 | Storch, Gregory, Wylie, Kristine, Wylie, Todd
— Technology Description
A team of researchers at Washington University developed “ViroCap”, a patented capture probe technique for senistive, comprehensive, in-depth metagenomics analysis vertebrate viruses. This invention could enhance traditional metagenomics shotgun sequencing (MSS) w…
by | Jan 31, 2020 | Tolia, Niraj
— Plasmid comprising the signal peptide and extracellular domain of human glycophorin A fused to antibody Fc domain and a his tag. This plasmid has been used to study malaria treatments.
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