— An UPAB1 derivative, UPAB1p-, that spontaneously loss pAB5 was identified by detection of restored Hcp secretion and isolated via an ELISA.
Compared to wildype UPAB1, UPAB1p- displayed comparable growth in vitro in both rich medium and urine from healthy donors, indicating that less pAB5 did not in…
— Technology Description
Researchers in Prof. Mario Feldman’s laboratory have developed a patented, versatile, cost-effective platform for creating new multivalent vaccines for a variety of Gram-negative and Gram-positive bacteria. This technology, glycoengineered outer membrane vesicles (geOM…
— Background: Cardiovascular disease, including acute myocardial injury (AMI), is responsible for over 610,000 deaths per year in the US making it the number one cause of death. The gold standard for AMI diagnosis relies on determination of the cardiac troponin I (cTnI) plasma level. The rise in the l…
— Background: Vasodilatory shock, a reduction in effective blood circulation, occurs when endogenous vasoconstrictor mechanisms fail as a result of an often lethal combination of severe infections. Sepsis, as one of the causes, alone affects 1 million people resulting in more than 258,000 deaths each …
— Technology Description
Researchers in Dr. Perry Grigsby’s lab have developed a patented brachytherapy device for outpatient, MRI-guided treatment of gynecological cancers. Gynecological cancers, such as recurrent endometrial and cervical cancers, can be treated with brachytherapy, but requir…
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Creating...
