by | Oct 22, 2019 | Gordon, Jeffrey, Turnbaugh, Peter
— Technology Summary:
Obesity rates worldwide are increasing at an astounding rate. While diet, lifestyle, and physical activity have traditionally been identified as the main causative factors, researchers at Washington University are the first to implicate gut bacteria (microbiome) as a new drivin…
by | Oct 22, 2019 | Miner, Jeffrey
by | Oct 22, 2019 | Barratt, Michael, Chang, Hao-Wei, Gehrig, Jeanette, Gordon, Jeffrey, Venkatesh, Siddarth
— Technology Description
Prof. Jeffrey Gordon and his colleagues have developed an inexpensive food formulation that could treat malnutrition and a range of associated health problems by repairing the gut microbiome. Children who are malnourished are currently treated with supplemental nutrition tha…
by | Oct 22, 2019 | Blumer, Kendall, Onken, Michael
— Disease indication – Uveal melanoma and other G protein-driven disorders, including other cancers (certain vascular tumors, colon, lung, adenocarcinoma, skin melanoma, thyroid adenoma), cholera and Sturge-Weber Syndrome
Drug format – small molecule (FR900359, a bioavailable inhibitor of…
by | Oct 22, 2019 | Mennerick, Steven, Sun, Min-Yu, Taylor, Amanda, Zorumski, Charles
— Disease indication – neuroprotection in stroke/ischemia with potential for treating other neurodegenerative diseases
Drug format – neurosteroid
Drug class – drug repurposing (25-hydroxycholesterol)
Research stage and Preliminary data:
In vitro – The inventors demonstrated…