Summaries by Inventor DeSelm, Carl

Chimeric antigen receptor dendritic cells
DeSelm, Carl
T-019199

— Technology Description Researchers at Washington University in St. Louis have developed a genetic method to produce chimeric antigen receptor dendritic cells (CAR-DCs) for the treatment of solid tumors. The team generated a CAR that drives differentiation of cDC1s and mediates tumor-specific uptak…

CAR Macrophages for Targeted Degradation of Pathogenic Substances
DeSelm, Carl ; Diwan, Abhinav ; Lee, Jin-Moo
T-020543

— Published Date: 5/14/2025 Value proposition: Self-sustaining chimeric macrophages as a novel approach to target amyloid plaques resulting in improved efficacy and survival in patients. Technology Description Researchers from Washington University in St. Louis have engineered macrophages to expre…