Summaries by Inventor DiAntonio, Aaron

Modulation of the DLK/JNK Pathway as a Method for Inhibiting Axonal Degeneration
DiAntonio, Aaron ; Milbrandt, Jeffrey ; Miller, Bradley ; Press, Craig
T-008422

— Background: Axonal degeneration is a feature commonly associated with many neuropathological conditions including response to injury, exposure to neurotoxins, hereditary neuropathies, glaucoma, and neurodegenerative diseases. The degenerative process is active when neuronal insults trigger a self-de…

New Strategy for Treatment of Neurodegenerative Diseases with Axonopathy
DiAntonio, Aaron ; Geisler, Stefanie ; Mao, Xianrong ; Milbrandt, Jeffrey ; Summers, Daniel
T-017543

— Value Proposition: This invention uses a novel gene therapy that blocks the axon degeneration typical of neurodegenerative diseases. Technology Description Researchers at Washington University in St. Louis have developed a new strategy for treatment of neurodegenerative diseases with axonopathy…

Crispr developed SARM1 Knockout Rat
DiAntonio, Aaron ; Milbrandt, Jeffrey
T-018728

— Crispr developed SARM1 Knockout Rat

 

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