Summaries by Inventor Dugan, Laura

PET Radiotracers for Imaging Free Radicals and Reactive Oxygen Species (Materials: WC-4-77)
Chu, Wenhua ; Dugan, Laura ; Mach, Robert ; Mintun, Mark
T-009254

— Many diseases can be associated with abnormal production of reactive oxygen species (ROS) due to oxidative stress. Currently there is no way to image this in situ. Dihydroethidium (DHE) naturally produces a fluorescent product when oxidized by an ROS. The signal is not strong enough for practical im…