Summaries by Inventor Ellebedy, Ali
Ellebedy, Ali
T-019707
— Disease indication – SARS-CoV-2 infection (COVID-19) Drug format Drug class – Best-in-class Research stage and Preliminary data – The inventors have developed and characterized these antibodies, creating a chimeric version with a human IgG backbone for SARS2-38. The antibodies have …
Anti-Influenza HA monoclonal antibodiesEllebedy, Ali
T-019529
— Panel of 300 recombinant human monoclonal antibodies that are directed against influenza virus HA. These antibodies were derived from plasmablasts and germinal center B cells that were isolated from three healthy volunteers after influenza vaccination. Turner, J. S., Zhou, J. Q., Han, J., Schmitz, …
Mouse monoclonal antibodies against SARS-CoV-2 nucleocapsid proteinEllebedy, Ali
T-019510
— These are six monoclonal antibodies specific to SARS-CoV-2 Nucleocapsid protein that could potentially be used for COVID-19 diagnostics.
Broadly cross-reactive anti-HA stalk antibodiesEllebedy, Ali
T-019212
— Six recombinant human monoclonal antibodies that are directed against the conserved stalk region of influenza virus HA. This stalk region is currently being assessed as a potential candidate as a universal influenza vaccine. These antibodies can be used as diagnostics and also as validation tools fo…
Human monoclonal antibodies against SARS-CoV-2 nucleocapsid proteinEllebedy, Ali
T-019492
— Species: Human Target: SARS-CoV-2 nucleocapsid protein Applications: Description: Two recombinant fully human monoclonal antibodies that recognize SARS-CoV-2 spike protein (data below). Related Web Links: Ellebedy Profile; Ellebedy Lab
Mouse monoclonal antibodies against SARS-CoV-2 spike protein (Ellebedy)Diamond, Michael ; Ellebedy, Ali ; Fremont, Daved
T-019438
— Species: Mouse Target: SARS-CoV-2 spike protein Applications: Description: Four murine monoclonal antibodies that recognize SARS-CoV-2 spike protein. Data below includes avaiable antibodies (mCoV.1.1C02; mCoV.1.2C08; mCoV.1.2D09; mCoV.1.2F05). Related Web Links: Ellebedy Profile; Ellebedy Lab …
Human monoclonal antibodies against SARS-CoV-2 spike proteinEllebedy, Ali ; McIntire, Katherine ; Mudd, Philip ; Schmitz, Aaron ; Turner, Jackson
T-019454
— Species: Human Target: SARS-CoV-2 spike protein Applications: Description: Ten recombinant fully human monoclonal antibodies that recognize SARS-CoV-2 spike protein (data below). Related Web Links: Ellebedy Profile; Ellebedy Lab Available Antibodies mAb name Ag 30.0000 10.0…
Human Monoclonal Antibodies: MD.03.1H06, MD.03.1B06, MD.03.1D11, MD.031F03, MD.03.1F11, MD.03.1H01, MD.025.2H09, MD.03.1G01, MD.025.2F10, MD.025.2B07, MD.025.2G11, MD.025.1F09, MD.025.1D01, MD.025.1H07, 306.012.7.1C10, 306.012.7.1A05, 10.036.7.1B04, 10.04.7.1B03Ellebedy, Ali
T-018756
— Human Monoclonal Antibodies: MD.03.1H06, MD.03.1B06, MD.03.1D11, MD.031F03, MD.03.1F11, MD.03.1H01, MD.025.2H09, MD.03.1G01, MD.025.2F10, MD.025.2B07, MD.025.2G11, MD.025.1F09, MD.025.1D01, MD.025.1H07, 306.012.7.1C10, 306.012.7.1A05, 10.036.7.1B04, 10.04.7.1B03
Human Monoclonal Antibodies for Influenza VirusEllebedy, Ali
T-019018
— These are recombinant human monoclonal antibodies that are directed against two conserved internal proteins of the influenza virus.
Chimeric murine anti-FimH Monoclonal AntibodiesEllebedy, Ali
T-019117
— These are recombinant chimeric murine monoclonal antibodies that are directed against FimH, an adhesin within uropathogenic E coli (UPEC). The monoclonal antibodies were isolated from mice immunized with adjuvanted FimCH, but are expressed on a human IgG1 backbone and hence they are chimeric.
Uropathogen VaccinesDodson, Karen ; Ellebedy, Ali ; Feldman, Mario ; Hultgren, Scott ; Pinkner, Jerome ; Tamadonfar, Kevin ; Timm, Morgan
T-020120
— Technology Description Researchers in Scott Hultgren’s laboratory at Washington University have created two prospective vaccine treatments designed to prevent the colonization of prominent uropathogens. These vaccines have potential for treating urinary tract infections (UTIs) with specific m…