Summaries by Inventor Imoukhuede, Princess
Mutant PDGF-B as a VEGFR inhibitor
Imoukhuede, Princess
T-018996
Imoukhuede, Princess
T-018996
— Technology Description Researchers in the Imoukhuede lab at Washington University have developed a library of mutant PDGF-B proteins to develop more effective VEGF pathway inhibitors. As PDGF-B also binds to VEGF receptors, a mutant form can be used to block VEGF binding and stop tumor angiogenesi…