Summaries by Inventor Karpova, Darja

HoxB5 cDTR mice
DiPersio, John ; Karpova, Darja
T-018897

— Transgenic HoxB5 conditional DTR (cDTR) mice have been generated using CRISPR mediated targeting of the HoxB5 gene (exon2) in fertilized wildtype C57Bl/6 eggs that were then microinjected into pseudopregnant wildtype female mice. The construct targeted under the controls of the endogenous HoxB5 prom…