Summaries by Inventor Krchma, Karen

A novel modulator of tumor angiogenesis and anti-tumor immunity
Choi, Kyunghee ; Kabir, Ashraf Ul ; Krchma, Karen
T-019294

— Technology Description Researchers in Kyunghee Choi’s lab at Washington University in St. Louis have identified a novel target, Myct1, that modulates tumor angiogenesis and anti-tumor immune response. Myct1 inhibition with siRNA blocks angiogenesis and promotes infiltration of cytotoxic T ly…

Zbtb46, a novel target for cancer therapy
Choi, Kyunghee ; Kabir, Ashraf Ul ; Krchma, Karen
T-020458

— T-020458 — Zbtb46, a novel target for cancer therapy Technology Description Solid neoplasms are difficult to treat using immune checkpoint inhibitors in part because of the immunosuppressive nature of the tumor microenvironment. Researchers at Washington University School of Medicine, led b…