Summaries by Inventor Liu, Xianyu

MOR1D Mediates Opioid and Liver Disease-Induced Itch via GRPR
Chen, Zhou-Feng ; Liu, Xianyu
T-011473

— Background: Opioids, such as morphine, are used in pain management and have significant analgesic effects. However a common side effect of morphine is severe itching. Currently, morphine-induced itch is treated with antagonists against the mu opioid receptor. While these antagonists reduce itch, the…