Summaries by Inventor Murphy, Theresa

Modulation of Lymphocyte Activity
Murphy, Kenneth ; Murphy, Theresa ; Watanabe, Norihiko ; Yang, Jianfei
T-004061

— Background: B and T lymphocyte attenuator (BTLA or CD272) is an inhibitory receptor expressed on T and B cells, dendritic cells and select myeloid cells. BTLA interacts with costimulatory molecule herpesvirus entry mediator (HVEM, Tnfrsf14, ATAR, HVEA, LIGHTR, or TR2). When bound to BTLA, HVEM atten…

B6.129.Btla tm1kmm/J Mouse
Murphy, Kenneth ; Murphy, Theresa
T-014100

— Notes: Btla-/- knockout mouse with a 129S/SvEv background. B6.129.Btla tm1kmm/J Mouse.

Xcr1 IRES mCherry-hCre Mouse Strain
Durai, Vivek ; Murphy, Kenneth ; Murphy, Theresa
T-019142

— Xcr1 IRES mCherry-hCre Mouse Strain This genetically modified mouse strain expresses the fluorescent marker mCherry and a human codon optimzed Cre in the same transcript as the chemokine receptor XCR1. XCR1 is specifically expressed in cDC1s, allowing specific deletion of genes in and the fluoresce…

Knockout Mouse lacking Expression of the Batf3 Gene
Diamond, Michael ; Murphy, Kenneth ; Murphy, Theresa ; Schreiber, Robert ; Unanue, Emil
T-009136

— Notes: Batf3-/- knockout mouse with a 129SvEv background.