Summaries by Inventor Shao, Jieya

Monoclonal antibodies against pSer784-VCP
Shao, Jieya
T-019491

— VCP is an essential AAA+ ATPase that regulates proteostasis under normal and stressed cellular conditions. These monoclonal antibodies specifically recognize pSer784-VCP, which is phosphorylated during the DNA damage response and plays a crucial role in cellular survival upon genotoxic chemotherapy …

Biomarker to predict cancer response to chemotherapy
Diamond, Marc ; Shao, Jieya
T-015631

— Technology Description Researchers at Washington University in St. Louis have developed a prognostic biomarker that can be used to predict response to genotoxic chemotherapy for patients with basal-like/triple-negative breast cancer. Basal-like/triple-negative breast cancer is considered to be mor…