Summaries by Inventor Virgin, Herbert
Loh, Joy ; Stappenbeck, Thaddeus ; Thackray, Larissa ; Virgin, Herbert ; Wang, David ; Yokoyama, Christine ; Zhao, Guoyan
T-012077
— Background: Mice are critical animal models for scientists investigating both basic and applied research principles. Several novel murine astroviruses have been identified in mouse facility at Washington University School of Medicine. Astroviruses are RNA viruses often associated with gastrointestin…
Novel human astrovirus sequences for diagnostics and vaccine development for encephalitis and gastroenteritisFinkbeiner, Stacy ; Virgin, Herbert ; Wang, David ; Zhao, Guoyan
T-009294
— Technology Description A team of researchers at Washington University and the Centers for Disease Control discovered, sequenced and patented a novel human astrovirus that can cause encephalitis and gastroenteritis (non-etiologic diarrhea), offering a path to detection and diagnostics. The virus (…
Lrp1 and the Blood Brain BarrierAmarasinghe, Gaya ; Ganaie, Safder ; Leung, Daisy ; Virgin, Herbert
T-019577
— T-019577 – Lrp1 and the blood brain barrier Technology Description Researchers in Gaya Amarasinghe’s laboratory at Washington University have engineered new protein fragments (RVFV Gn) to target LRP1, which was recently identified as an essential entry factor for Rift Valley Fever Virus (RVF…
