Summaries by Inventor Wang, Lihong

Optical Resolution Photoacoustic Imaging Device for Port-Wine Stains
Maslov, Konstantin ; Rao, Bin ; Wang, Lihong
T-012585

— A photoacoustic tomography device that provides high optical absorption contrast with high lateral resolution, including very good melanin distribution images, for port wine stain birthmarks.

Photon tunneling
An, Woo Jin ; Wang, Lihong
T-012515

— Photon tunneling has the potential to guide light to the core of a human body in vivo. Imaging, sensing, and therapy are among the applications for this technology. Light, as opposed to potentially harmful x-rays, is an ideal non-ionizing radiation for imaging and treating biological tissue, however…

Compressed-sensing Ultrafast Photography (CUP)
Gao, Liang ; Liang, Jinyang ; Wang, Lihong
T-014733

— Compressed-sensing ultrafast photography (CUP) is an ultrafast imaging technique that can capture non-repetitive, time-evolving events at up to 100 billion frames per second. Compared to existing ultrafast imaging methods, CUP has a prominent advantage in measuring an x, y, t (x, y, spatial coordina…

Reversibly switchable photoacoustic tomography using a bacterial phytochrome as a genetically encoded near-infrared photochromic probe
Li, Lei ; Wang, Lihong ; Yao, Junjie
T-015670

— The invention is a novel photoacoustic imaging technique, termed reversibly switchable photoacoustic tomography (RS-PAT). It exhibits a large penetration depth, a high detection sensitivity, and a spatial super-resolution. The most important feature of this technique is that it significantly incre…

Grueneisen-memory photoacoustic microscopy
Wang, Lidai ; Wang, Lihong ; Zhang, Chi
T-014165

— Lihong Wang, Professor at Washington University in St. Louis, is a pioneer in the field of Photoacoustic (PA) Imaging. His innovations have enabled non-invasive imaging of living organisms at scales ranging from subcellular to whole-body at depths and resolutions that are simply impossible with any …

Optical Coherence Computed Tomography
Li, Li ; Wang, Lihong
T-008832

— Optical coherence tomography (OCT) utilizes optical light to obtain an image of opaque or translucent objects, ie tissue. Because scattered light contributes to the bluring found in other optical imaging techniques, OCT filters out all the scattered light. An image is formed using only the back refl…

Multi-focus optical-resolution photoacoustic microscopy with ultrasonic array detection
Maslov, Konstantin ; Rao, Bin ; Song, Liang ; Wang, Lihong
T-010922

— In clinical practice, high imaging speed is critical to reduce motion artifacts, cost, and patient discomfort. Researchers at Washington University have developed multi-focal optical-resolution photoacoustic microscopy (MFOR-PAM) capable of high-resolution imaging of hemoglobin concentration and oxy…

Transcranial photoacoustic/thermoacoustic tomography brain imaging informed by adjunct image data (combined with 013043)
Anastasio, Mark ; Huang, Chao ; Nie, Liming ; Schoonover, Robert ; Wang, Lihong
T-013450

— Existing high-resolution human brain imaging modalities such as X-ray computed tomography (CT) and magnetic resonance imaging (MRI) are expensive and employ bulky and generally non-portable imaging equipment. Moreover, X-ray CT is unsafe for patients who need long time monitoring of brain diseases …