Summaries by Inventor Yu, Lihai

Tri-heterocyclic ring compounds as alpha-synuclein ligands
Kotzbauer, Paul ; Mach, Robert ; Tu, Zhude "Will" ; Yu, Lihai
T-011942

— A novel series of phenothiazine-derived molecules are useful for detecting Parkinson’s disease using positron emission tomography (PET) imaging. The molecules bind with high affinity to the alpha- synuclein protein, which forms aggregates in the brain and is associated with the neurodegenerati…