Clifednamide A and C are congeners of long known ikarugamycin. Ikarugamycin has anti-inflammatory, anti-ciliate, plant modulatory and other desirable bioactivities. These clifednamide compounds may also have therapeutic, industrial or agricultural value.

Publication: Qi, Y., Ding, E., & Blodgett, J. A. (2018). Native and engineered clifednamide biosynthesis in multiple Streptomyces spp. ACS synthetic biology, 7(2), 357-362.