Gastrin-releasing peptide (GRP) functions as neurotransmitter for non-histaminergic itch. This mouse line has the Cre gene knocked into Grp locus and could be used for studies of GRP function in different tissues.

Barry, D. M., Liu, X. T., Liu, B., Liu, X. Y., Gao, F., Zeng, X., … & Tao, A. (2020). Exploration of sensory and spinal neurons expressing gastrin-releasing peptide in itch and pain related behaviors. Nature Communications, 11(1), 1-14.