by | Jan 5, 2026 | Dai, Yifan, Pappu, Rohit
— Published date: 1/6/2025
Value Proposition: Directed evolution of synthetic intrinsically disordered proteins for condensate editing.
Technology Description
Researchers at Washington University in St. Louis have developed a directed evolution method and selection strategies to enable the evolut…
by | Jan 5, 2026 | Boon, Adrianus "Jacco", Dai, Yanan, Fremont, Daved, Harastani, Houda
— Published date: 1/6/2025
Value Proposition: Stabilization of glycoprotein of Bourbon Virus (BRBV) and related thogotoviruses as a key target for vaccine and antiviral development.
Technology Description
Researchers at Washington University in St. Louis have determined the pre-fusion structure…
by | May 13, 2025 | Djuranovic, Sergej, Pirzada, Mujeeb
— Published Date: 5/14/2025
Value proposition: Novel ASOs that increase key protein production to limit neurodegeneration caused by ALS and frontotemporal dementia (FTD).
Technology Description
TDP-43 pathology is present in ~97% of ALS, ~50% of FTD, and frequently observed in other neurodegenerat…
by | May 13, 2025 | Cavalli, Valeria, Feng, Rui
— Published Date: 12/21/24
Value proposition: A cost-effective, drug-based therapy targeting the endothelin B receptor (ETBR) to promote peripheral nerve regeneration, offering improved recovery and compatibility with existing treatments.
Technology Description
Researchers at Washington University…
by | Jan 8, 2025 | Dantas, Gautam, Gorushi, Olivia, Helmink, Beth, Kwak, Suryang, Prusa, Jerome, Wallace, Miranda
— Published date: 1/9/2025
Value Proposition: Genetically engineered yeast used to treat gastrointestinal tumors through the delivery of immune checkpoint inhibitor (ICI) proteins.
Technology Description
Researchers at Washington University in St. Louis have developed a genetically engineered …