— Neurosteroids are of great interest because of their ability to alter brain function. Compounds of the type disclosed here have potential to be new drugs useful for causing anesthesia and treating depression, anxiety, sleep disorders, seizures.
— Background: Severe itch (or pruritus) is associated with multiple diseases such as liver disease, non-Hodgkin’s lymphoma, psoriasis, and common eczema and is also a side effect of many treatments including analgesics (like morphine) and renal dialysis. Chronic pruritus is a top reason for derm…
— The present hydrogel technology can be used as a lens replacement material for the permanent treatment of cataracts and presbyopia as well as a vitreous substitute. This co-polymeric hydrogel system can be reversibly converted between a hydrogel in the oxidized state and a solution in the reduced st…
— Urinary tract infection (UTI) caused by uropathogenic Escherichia coli (UPEC) is one of the most common infectious diseases in women. The morbidity and economic impact are enormous, with over $2.5 billion spent annually on treatment. The high rates of recurrence, and the large numbers of women that …
— Oropharyngeal squamous cell carcinoma (OSCC) rates have increased significantly in recent years, and because of the different underlying causes of the disease no single treatment regime seems to be advantageous over another. Currently, the prognosis of OSCC is based on clinical features of the OSCC…
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