Mouse embryonic fibroblasts from IRF 3/5/7 knock out animals

— Mouse fibroblasts are isolated from Irf3-/-xlrf5-/-xlrf7-/-TKO mice. Researchers generated the mouse strains from an inbred C57BL/6 background.

Associated Publication: IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling

αB-crystallin (cryAB) R120G mutant knock-in mice

— Researchers developed these knock-in mice by using homologous recombination to clone the R120G mutation into exon 3 of the αB-crystallin gene (cryab). αB-crystallin (cryAB) helps to maintain protein stability in the eye lens, which is necessary for transparency. The R120G mutation causes…

MOG.15 hybridoma

— MOG.15 is a T cell hybridoma that will be active when engaged with an antigen presenting cell that is presenting MOG35-55 peptide.

Publication: Conditional MHC Class II Expression Reveals a Limited Role for B Cell Antigen Presentation in Primary and Secondary CD4 T Cell Responses

Adenovirus: Ad-GFP-LC3, Ad-FLAG-BNIP3, Ad-mBECLIN-1, Ad-Parkin(HA), Ad-TRAF2(FLAG), Ad-TRAF2-Rm, Ad- TRAF2-deltaN. Plasmids: mCherry-GFP-LC3, DsRed-BNIP3, GFP-Parkin, GFP-LC3, DsRed-monomer-GFP fusion positive control

— Adenoviruses were generated using the Invitrogen Virapower system, which uses Clonase mediated recombination. They were generated in HEK293A cells and titered per the manufacturer’s instructions.

Publications: Enhancing lysosome biogenesis attenuates BNIP3-induced cardiomyocyte death; Impaired …

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