by | Oct 22, 2019 | Finkbeiner, Stacy, Virgin, Herbert, Wang, David, Zhao, Guoyan
— Technology Description
A team of researchers at Washington University and the Centers for Disease Control discovered, sequenced and patented a novel human astrovirus that can cause encephalitis and gastroenteritis (non-etiologic diarrhea), offering a path to detection and diagnostics.
The virus (…
by | Oct 22, 2019 | Curiel, David
— Disease indication – Cancer
Drug format – Adenoviral vector for immunotherapy/dendritic cell therapy
Drug class – Improvement
Research stage and Preliminary data:
Target – Carbohydrate biomarkers of cancer
Background:
Dendritic cells (DCs) are potent antigen presenting cell…
by | Oct 22, 2019 | Colonna, Marco
— Target: Cluster of Differentiation, a.k.a. Neural Cell Adhesion Molecule.
Notes: Clone name is DCN.70.
by | Oct 22, 2019 | Kharasch, Evan, Morrissey, Jeremiah, Singamaneni, Srikanth, Tadepalli, Sirimuvva
— Technology Description
An interdisciplinary team of researchers at Washington University have developed a sensitive, shelf-stable, label-free system for quickly quantifying biomarkers in point-of-care settings (e.g., office, ambulance or battlefield). Localized surface plasmon resonance (LSPR) off…
by | Oct 22, 2019 | Colonna, Marco, Ulland, Tyler
— Background: Alzheimer’s disease (AD) is the 6th leading cause of death in the United States, and yet causation of the disease is poorly understood and targets for therapeutic intervention are still being identified. Recently, mutations in the immune receptor TREM2 have been found to be strongl…