Armenian hamster anti-mouse TCR Vb 8.3 IgG3 monoclonal antibody (clone 1B3.3)

— Target: Full length mouse Vb 8.3 TCR but not 8.1 or 8.2. Vb 8.3.

Application: Flow cytometry

This antibody was made by immunizing Armenian hamsters. It was used to study the mechanisms that act to keep only one functional TCR beta-chain per cell and the effect of selecting ligand density on positive selection and endogenous receptor usage in mice.

Publication: TCR transgenic mice in which …

Murine Hybridoma producing Monoclonal Antibodies against Human NKp44

— Target: NKp44 is a novel triggering surface molecular specifcially expressed by activated natural killer cells.

Notes: Clone name 448.189 Marco Colonna, MD

Inventors generated NKp44 monocolonal antibodies by immunizing mice with a NKp44-human crystallizable fragment (Fc) fusion protein. The antibodies have been used to study innate and adaptive immune responses.

Publication: Paradoxic inhibition of human natural interferon-producing cells by the activ…

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