by | Nov 6, 2019 | Atkinson, John, Molina-Vicenty, Hector
— Crry-knockout mouse strain (Crry -/-)
Researchers generated mice deficient in Crry by disrupting exon 5 of the mouse Crry gene. The mice are sensitive to complement deposition and activation, especially the C3 component of complement on the surface of the placenta.
Publication: A Critical Role for Murine Complement Regulator Crry in Fe…
by | Nov 6, 2019 | Chaplin, David, Schreiber, Robert, Unanue, Emil
— Target: Mouse/rat interleukin-1 beta and mouse interleukin-1 alpha. Located on macrophages, dendritic cells, T and B cells.
Notes: Clone name is B-122 and Alf-161
Information on antibodies against IL-1 beta:
The role of murine IL-1 beta in vitro and in vivo has not been defined. We describe here the production of neutralizing and immunoprecipitating mAb and polyclonal antibodies specific for murine IL-1 beta and their application to a characterization of the…
by | Oct 30, 2019 | Chaplin, David, Ferguson, Thomas
— Mouse strain deficient in IL-1 beta
Inventors created the IL-1 beta deficient mouse strain by targeting the IL-1 beta gene in embryonic stem cells. These mice develop and grow normally. Endotoxin-stimulated peritoneal macrophages from IL-1beta- deficient mice showed normal synthesis and cellular release of IL- 1alpha after treatment w…
by | Oct 22, 2019 | Murphy, Kenneth, Murphy, Theresa
— Notes: Btla-/- knockout mouse with a 129S/SvEv background. B6.129.Btla tm1kmm/J Mouse.
by | Oct 22, 2019 | Diamond, Michael, Murphy, Kenneth, Murphy, Theresa, Schreiber, Robert, Unanue, Emil
— Notes: Batf3-/- knockout mouse with a 129SvEv background.
Creating...
