by | Oct 22, 2019 | Klechevsky, Eynav
— The monoclonal antibodies developed are agaonistic monoclonal antibodies. These antibodies can help in enhancing the immune system by activating dendritic cell subsets. Furthermore, these antibodies are unique, as they can activate Dendritic cells without the need for cross-linking the receptor.
by | Oct 22, 2019 | Klechevsky, Eynav
— Background
Dendritic cells (DCs) are antigen-presenting cells that are essential to the adaptability of the immune system. Several subsets of DCs have been identified in tissues that interface with the environment (e.g. skin, mucosal lining). While the role of specific DC subsets are unknown, DCs p…
by | Oct 22, 2019 | Murphy, Kenneth, Murphy, Theresa
— Notes: Btla-/- knockout mouse with a 129S/SvEv background. B6.129.Btla tm1kmm/J Mouse.
by | Oct 22, 2019 | Diamond, Michael, Murphy, Kenneth, Murphy, Theresa, Schreiber, Robert, Unanue, Emil
— Notes: Batf3-/- knockout mouse with a 129SvEv background.
by | Jul 31, 2018 | Tobin, Garry
— Technology Description: A hospital-based algorithm and associated software that is able to predict which in-patients on diabetic therapy will develop hypoglycemia. It is able to predict in real time which patients are at risk and alert MDs to start interventions to prevent possible side effects or d…